Real Dictionary

slough
verb: When a plant sloughs its leaves, or an animal such as a snake sloughs its skin, the leaves or skin come off naturally.

slough in American English 1
the skin of a snake, esp. the outer layer that is periodically cast off
to be shed, cast off, or discarded; come off
noun: an area of soft, muddy ground; swamp or swamplike region

slough in American English 2
a place, as a hollow, full of soft, deep mud
intransitive verb: to be or become shed or cast off, as the slough of a snake
noun: the outer layer of the skin of a snake, which is cast off periodically
transitive verb: to dispose or get rid of; cast

Slough in British English
noun: an industrial town in SE central England, in Slough unitary authority, Berkshire; food products, high-tech industries. Pop: 126 276 (2001)

slough in British English 1
noun: a hollow filled with mud; bog

slough in British English 2
noun: any outer covering that is shed, such as the dead outer layer of the skin of a snake, the cellular debris in a wound, etc
verb: to shed (a skin, etc) or (of a skin, etc) to be shed