Real Dictionary

Lyme disease in American English
an acute inflammatory disease caused by a tick-borne spirochete, Borrelia burgdorferi, characterized by recurrent episodes of decreasing severity in which joint swelling, fever, and rash occur, sometimes with cardiac or nervous system complications
an acute, recurrent, inflammatory disease caused by a spirochete (Borrelia burgdorferi) transmitted by certain ticks (esp. Ixodes dammini), characterized at first by a skin rash, headache, fever, etc. and later by arthritis, neurological damage, and cardi

Lyme disease in British English
noun: a disease of domestic animals and humans, caused by the spirochaete Borrelia burghdorferi and transmitted by ticks, and variously affecting the joints, heart, and brain